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The modern history of smoking has so far seen many changes, with the latest change in its social standing being the introduction of e-cigarettes (also known as vapes)

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This leads to the development and increased severity of respiratory infections for both healthy people and patients with chronic obstructive pulmonary disease (COPD), a condition commonly associated with smoking

Reviewed August 2025 Speak with a doctor for up-to-date and personalised medical advice.

Cell Culture and Agents Human bronchial epithelial (HBE) cells were purchased from American Type Culture Collection (ATCC, CRL-2741), and were maintained in RPMI 1640 with 10% FBS, 50 U/mL penicillin, and 50 U/mL streptomycin